Isabel Healthcare

Isabel Healthcare's mission is to improve the quality of patient care by providing clinicians with decision support and knowledge to reduce diagnosis errors.

Isabel Healthcare is a fast growing, venture capital backed company operating on a global basis. The company is best known for Isabel, an award-winning Web-based, diagnosis decision support system called Isabel which uses cutting edge technology from Autonomy, an industry leader in Meaning Based Computing (MBC) coupled with proprietary Isabel algorithms to 'understand' vast amounts of medical knowledge. This enables the system to instantly provide the busy clinician with a safe checklist of likely diagnoses for a set of signs and symptoms entered in free text. The clinicians who 'Isabel' their patients at an early stage are able to offer a higher quality of care and reduce clinical risk by ensuring that important possible diagnoses have not been missed.

Using the same proprietary technology which powers the diagnosis reminder system, Isabel also mobilizes knowledge to help the clinician find relevant and diagnosis specific answers to clinical questions more easily and quickly at the point of care.

As well as helping clinicians provide the highest quality standard of care, Isabel has set new standards for the clinical testing of decision support systems in healthcare having undergone a robust, peer-reviewed validation process over 7 years to demonstrate its accuracy, effectiveness and value. To date, 13 articles including independent clinical studies, multi-centre collaborative studies, and our own studies as developers have appeared in prestigious peer-reviewed journals.

Isabel uniquely adds intelligence to the electronic medical record (EMR) by processing extracted relevant clinical information automatically thereby providing the clinician with diagnosis support instantly with no additional data entry. To date, Isabel interfaces with NextGen, PatientKeeper and A4 Health Systems, along with a number of hospital-based EMR vendors including Cerner.

Jason and Charlotte Maude founded Isabel Healthcare in July 1999 together with Joseph Britto MD. Dr. Britto was the Attending Physician on the Pediatric Intensive Care Unit (PICU) at St Mary’s Hospital in Paddington, London that handled the Maude's three-year old daughter's care after she was nearly fatally misdiagnosed by her local hospital. Isabel spent two months in the hospital, including a month in the PICU after experiencing multiple organ failure and cardiac arrest.

Isabel’s extensive suffering could have been avoided if the local emergency department and family physicians had stopped to ask 'what else might this be?' rather than assuming her symptoms as typical of the chicken pox from which she was also suffering. Isabel was later diagnosed by Dr. Britto to be suffering from well described complications of chicken pox-Toxic Shock Syndrome and Necrotising Fasciitis.

Rather than suing the hospital for the error, Jason Maude teamed up with Dr. Joseph Britto, who conceived the structure of the Isabel and has led the development of the Isabel clinical diagnosis decision support system. Isabel Healthcare was created, in honor of Isabel Maude and all patients whose lives have been impacted by missed or delayed diagnosis, to help clinicians around the world reduce cognitive diagnostic errors.

After two years of research and validation led by P. Ramnarayan MD the pediatric version of the Isabel diagnostic tool was launched in June 2002. With support from the UK Department of Health, the UK National Health Service and other key medical institutions, Isabel quickly gained credibility and support from around the world.

Within months of its launch, the system attracted more than 20,000 users from over 100 countries. Impressed with the system's high levels of speed and accuracy, demand rapidly grew for an adult version which was launched in January 2005 and is now used by many top-rated hospitals in the United States and around the world

Joseph Britto MD.
Chief Executive Officer and Co-founder, Isabel Healthcare, Inc.

As Chief Executive Officer and Co-founder of Isabel Healthcare, Inc., Dr. Joseph Britto brings more than 15 years of extensive medical knowledge to the company. Dr. Britto earned his Doctorate in Pediatrics in 1990 from the medical school at Bombay University. Three years later, as a Fellow and Lecturer at Imperial College School of Medicine at St. Mary's Hospital, Dr. Britto developed and validated England's first model of specialized inter-hospital transport of critically ill children. This resulted in greatly improved outcomes of hundreds of critically ill children transported each year. Dr. Britto's distinguished career continued and in 1996 he was recognized with the prestigious appointment of Attending Physician and Senior Lecturer. As a leading member of the pediatric intensive care team, Dr. Britto brought about dramatic reductions in the mortality rate of life threatening infections in critically ill children.

After caring for Isabel Maude in 1999, Dr. Britto co-founded Isabel Healthcare with Jason Maude and conceived the structure of the Isabel clinical diagnosis decision support system. Committed to leading the clinical, development and technical aspects of Isabel Healthcare, Dr. Britto chose to leave his distinguished clinical and academic career.

Dr. Britto has published more than 50 peer-reviewed papers and lectured extensively about pediatric critical care, life threatening infections, diagnosis errors and diagnosis decision support.

Dr. Joseph Britto is based in Reston, Virginia.

Jason Maude
Chief Executive Officer and Co-founder, Isabel Healthcare Ltd, UK.

Jason Maude serves as Chief Executive Officer and Co-founder of Isabel Healthcare Ltd. Prior to co-founding Isabel Healthcare Ltd, Maude spent 12 years working in the finance and investment banking industry in Europe. Throughout his career, Maude served as a top-ranked equity analyst at Kleinwort Benson Securities, Smith Barney and Dillon Read. While at Dillon Read, a prestigious U.S. investment bank, Maude served as partner and managing director of the company's UK office. This prominent position led Maude to AXA Investment Managers where he lead equity research and managed $500 billion global investment initiatives.

In 1999, Maude's three-year-old daughter, Isabel fell seriously ill, as a result of a misdiagnosis. Isabel's illness and experience inspired Maude to create Isabel Healthcare.

Jason Maude is based in Haslemere, UK.

P. Ramnarayan, MRCPCH, MD
Head of Research and Validation, Isabel Healthcare, Inc.

Dr. Ramnarayan joined Isabel Healthcare in 2000 after establishing the well-known Ram's Teaching Website, now at Medic Central. At Isabel, he has led the extensive and ground-breaking validation process to ensure Isabel's accuracy and ongoing capabilities.

Ramnarayan earned his M.D. from Imperial College and is currently an Attending Physician at Great Ormond Street Hospital for Children and St. Mary's Hospitals in London.

Amanda Tomlinson
Head of Content Management, Isabel Healthcare, Inc.

Amanda Tomlinson has been with Isabel Healthcare for nearly seven years. She joined the Company in 2000 after spending five years as a senior staff nurse on the Pediatric Infectious Disease ward at one of London's top hospitals. Tomlinson is focused on the development of the proprietary database, the tutored taxonomy and validation.

Natalie Cronje (Registered Dietitian)
Research Assistant, Isabel Healthcare, Inc.

Natalie Cronje has been with Isabel Healthcare since 2004. Prior to joining Isabel Healthcare she worked as a private practising Dietitian and lecturer at a prominent university in South Africa. Cronje is focused on validation, research and continued development of Isabel to ensure accuracy.

Ivan Briery
Co-founder of Voltaire Asset Management, London

Co Founder of Voltaire Asset Management, London -one of the UK's top performing equity hedge funds during 1998-2002 and formally a partner in Soros Funds.

Terry Hughes
Partner, Silver Point Europe

Silver Point Europe is a multi-billion dollar credit investment fund where Hughes heads the Principal Finance business.Prior to this he was a partner at Goldman Sachs where, over a ten year career, he undertook a variety of roles including heading the leveraged finance and private equity sponsor businesses within Europe. He was closely involved in many of the then defining deals such as financing of Vodafone's bid for Mannesmann and the original funding for the establishment of Orange. He also sat on Goldman Sach's Commitments Committee.

Andrew M. Kanter
Chief Operating Officer, Autonomy Corporation plc, London

Andrew M. Kanter joined Autonomy in August 2000 as Vice President, International Operations and Legal Affairs, and has served as their Chief Operating Officer since 2001. Prior to joining Autonomy, from July 1999 through July 2000, Mr Kanter was an associate attorney with Brobeck Hale and Dorr in London, England, primarily engaged in international mergers and acquisitions and corporate finance. From May 1997 through June 1999, Mr Kanter was an associate attorney in the Business & Technology group of Brobeck, Phleger & Harrison in San Francisco, CA, and prior to that was an associate attorney with Shearman & Sterling, San Francisco, CA. From August 1995 to July 1996 Mr Kanter was Clerk to Hon. Christine Miller of the U.S. Court of Federal Claims, Washington, DC. Mr Kanter holds a J.D. from the University of Southern California Law Center and a B.A. from Johns Hopkins University, and also studied at Kansai University of Foreign Studies, Osaka, Japan.

Juerg Schaeppi
CEO, Bank am Bellevue, Zurich, Switzerland

The Bellevue group is one of the world's leading healthcare investors managing $2 bn assets in BB Biotech and $1 bn in BB Medtech.

Jason Maude
CEO and Co-founder, Isabel Healthcare Ltd.

Jason Maude serves as Chief Executive Officer and Co-founder of Isabel Healthcare, Ltd. Prior to co-founding Isabel Healthcare Ltd., Maude spent 12 years working in the finance and investment banking industry in Europe. Throughout his career, Maude served as a top-ranked equity analyst at Kleinwort Benson Securities, Smith Barney and Dillon Read. While at Dillon Read, a prestigious U.S. investment bank, Maude served as partner and managing director of the company's UK office. This prominent position led Maude to AXA Investment Managers where he lead equity research and managed $500 billion global investment initiatives.

In 1999, Maude's three-year-old daughter, Isabel fell seriously ill, as a result of a misdiagnosis. Isabel's illness and experience inspired Maude to create Isabel Healthcare, Ltd.

Jason Maude is based in Haslemere, UK.

Joseph Britto, MD
CEO and Co-founder, Isabel Healthcare, Inc.

Dr. Britto has published more than 50 peer-reviewed papers and lectured extensively about pediatric critical care, life threatening infections, diagnosis errors and diagnosis decision support.

Dr. Joseph Britto is based in Reston, Virginia.