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Autonomy Congratulates Isabel on Government Funding

New investment from the Department of Health will enable extension of life-saving online clinical decision support and information system to full spectrum of adult medicine

CAMBRIDGE, UK - 3rd July, 2003 - Autonomy Corporation plc (Nasdaq: AUTN; LSE: AU.; Nasdaq Europe: AUTN) today congratulates The Isabel Medical Charity on receiving funding from the Department of Health and the Helen Hamlyn Trust that will enable the extension of its clinical decision support system to assist with the treatment of adult patients. ISABEL, which is based on Autonomy's sophisticated infrastructure software, was launched last year to bridge the knowledge gap that exists in many health systems, notably that most of the critical knowledge and experience resides with senior consultants in hospitals and not with the doctors who first examine patients.

ISABEL is a free of charge online clinical decision support system that is available to all registered health professionals, providing critical support in areas such as diagnosis, treatment guidelines and shared experience. ISABEL, which previously concentrated only on pediatrics, also offers an annotated image library, allowing users to compare their patients' visible symptoms with those available on the site, and consequently assist them in making a potentially life-saving diagnosis.

Autonomy donated its pattern-matching software to the Isabel Medical Charity to enable fast, accurate assistance for all medical professionals, who often do not have the benefit of the more specialist knowledge required to make accurate diagnoses. Applying Autonomy's pattern matching software to medical textbooks enables ISABEL to deliver a fast and practical differential diagnostic tool. When using ISABEL the doctor simply needs to type in a patient's symptoms from which the Autonomy software will extract the key ideas before searching ISABEL's extensive library of content to find a similar combination of symptoms - and consequently suggesting a range of relevant diagnoses. In essence, this mimics the doctor's existing and intuitive diagnostic process, the difference being that the system's base of textbook knowledge is far larger than can readily be stored in the human brain. Its performance is also unaffected by tiredness and overwork.

The charity's goals are primarily to reduce the number of people becoming seriously ill as a result of incorrect or delayed diagnosis, and to increase survival chances of sick children by ensuring that suitable treatment is administered immediately as a result of ready availability of expert guidelines compiled by acknowledged experts in specific fields of medicine. By June 2003, over 11,000 health professionals had registered with ISABEL, totaling over 110,000 page requests and more than 750,000 hits per month.

Mike Lynch, Founder and CEO of Autonomy Corporation today commented, "Autonomy is delighted that the hard work of the Isabel Medical Charity has been recognized in this way. ISABEL has a vital role to play in assisting healthcare professionals to make informed recommendations in necessarily short timescales."

Dr. Joseph Britto MD Clinical Director and Co-Founder, ISABEL Clinical Decision Support Systems today noted, "In recent DH funded trials at 4 NHS hospitals the ISABEL system has been shown to improve the diagnostic accuracy of frontline UK clinicians. ISABEL has been demonstrated to be unique not just in terms of the diagnostic tool, but in its ability to deliver into the workflow of the clinician treatment guidelines, lessons learnt from error and knowledge. Embedded in the planned UK national Electronic Patient Record the ISABEL system is likely to have a much bigger impact on morbidity and mortality."

Jason Maude, Trustee and Co-Founder of the ISABEL Medical Charity commented, "The diagnostic error made in my daughter's case was a dramatic example of how the model of healthcare delivery in the UK can go wrong. The ISABEL system has been shown to help clinicians improve patient care and safety and I am therefore delighted that the DH has confirmed additional financial support."

Autonomy's unique Intelligent Data Operating Layer (IDOL) integrates unstructured, semi-structured and structured information from multiple repositories through an understanding of their content. Autonomy grants enterprises the flexibility to use advanced information retrieval or legacy-based approaches. At the heart of Autonomy's software is its ability to process text, voice and video and identify and rank the main concepts within them. It then automatically categorizes, links, summarizes, personalizes and delivers that information. Autonomy's technology also drives collaboration across the enterprise and enables organizations to effectively leverage expertise. Autonomy's infrastructure technology is used to automate operations within enterprise information portals, customer relationship management, knowledge management, business intelligence and e-business applications, among others.

About ISABEL

Jason and Charlotte Maude founded the project in July 1999 together with Dr Joseph Britto, Paediatric Intensive Care Consultant at St Mary's Hospital, Paddington, London. Three months prior to this, the Maudes' 3-year-old daughter, Isabel, had spent a month in Intensive Care suffering multiple organ failure and cardiac arrest and a further month in a High Dependency ward. All this because her local A&E department and GP had failed to recognise her critical, life-threatening symptoms following chicken pox. Against all odds, Isabel's sole legacy is a large wound requiring extensive plastic surgery. During their time in hospital, the idea of a diagnostic tool slowly evolved during conversations between the Maudes and Dr Britto, who gradually gathered the support of a number of high profile doctors from hospitals around the country to make up the ISABEL team. The Isabel Medical Charity received charitable status in April 2000. Its registered office is in London. Further information is on the web at www.isabel.org.uk.

About Autonomy

Autonomy Corporation plc (Nasdaq: AUTN; Nasdaq Europe: AUTN; LSE: AU.) is a global leader in infrastructure software for the enterprise. Autonomy's technology powers applications dependent upon unstructured information including customer relationship management, knowledge management, enterprise portals, enterprise resource planning, online publishing and security applications. Autonomy's customer base includes more than 600 global organizations including AstraZeneca, BAE Systems, Ford, Ericsson, Hutchison 3G, the BBC, RoyalSunAlliance, Sun Microsystems and public sector agencies including the US Department of Defense, NASA and the US Department of Energy, as well as the UK Government's Department of Trade and Industry and numerous agencies responsible for homeland security related functions. Strategic reseller and OEM partners include leading companies such as ATG, BEA, Business Objects, Computer Associates, Hewlett Packard, IBM Global Services, Vignette, EDS and Sybase. The company has offices worldwide and is on the Web at www.autonomy.com.

Caution Concerning Forward-Looking Statements

With the exception of historical information, the matters set forth in this news release are forward-looking statements that involve risks and uncertainties. A number of important factors could cause actual results to differ materially from those in the forward-looking statements. These factors include, among others, technology risks, including dependence on core technology; fluctuations in quarterly results; dependence on new product development; rapid technological and market change; reliance on sales by others; management of growth; dependence on key personnel; rapid expansion; growth of the Internet; financial risk management; and future growth subject to risks. These factors and other factors, which could cause actual results to differ materially are also discussed in the company's filings with the United States Securities and Exchange Commission, including Autonomy's Annual Report on Form 20-F.

For more information, please contact:
Ian Black
Autonomy Corporation plc
+44 (0) 1223 448 000
ianb@autonomy.com
Jason/Charlotte Maude
ISABEL Medical Charity
+44 (0) 208 748 4330
info@isabel.org.uk
"The Clinical Knowledge Management suite of services leverages member capabilities, knowledge, information sources and networks to accelerate creating, identifying, spreading and sustaining health care improvements and innovations. We would have an extremely difficult time handling this wealth of information if were to rely on a manual system for tagging and delivering this information. Autonomy is the primary technology we use to automatically manage dynamic content sources across CKM, the Web and member hospitals."
Peggy Kjelgaard, VHA