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Isabel Products

At the heart of all the Isabel DDx systems is its cutting edge, proprietary Disease Pattern Recognition Engine Platform (DPREP). The engine is powered by innovative, statistical natural language processing software which understands the meaning and context of unstructured free text. This is applied to our medical database of disease presentations which comprises thousands of carefully selected, evidence-based documents describing the multiple ways that over 10,000 conditions can present. The engine has effectively been trained over almost two decades on virtually every known possible presentation of the majority of all known diseases. The initial results from the Isabel DPREP are then passed through an additional set of algorithms tuned over many years to ensure that only those results relevant to the patient’s age, gender and geographical region are displayed. It is this unique structure, very different from the more traditional rules based systems, which gives Isabel many inherent advantages:

  • Easy to use yet able to rapidly handle any permutation of clinical features

  • Scalability makes it easy to maintain, update and expand

  • Published API makes it easy to integrate into other systems

  • Platform structure enables the same core system to serve many different audiences from clinicians to patients and in multiple languages.


Benefitting from close to two decades of continuous development, validation and clinician feedback, Isabel today is widely acknowledged as the most accurate and versatile system available. When clinicians say they have ‘Isabeled’ a patient you know they have thought carefully about their diagnosis and are providing high quality, cost effective care.

Isabel Pro

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Isabel Pro for clinicians is the most powerful DDx generator on the market. Medical professionals around the world trust Isabel to broaden their differential diagnosis and aid their decision making. Isabel uniquely combines accuracy, ease of use and speed, covering over 10,000 conditions. Highly versatile with the ability to be used as a standalone system or fully integrated into other electronic systems, Isabel enables a seamless experience for clinicians.

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Isabel Symptom Checker

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The Isabel Symptom Checker (Isabel SC) for patients is the only symptom checker that allows a patient to describe their symptoms in their own words. Simple and easy-to-use, the system generates results in seconds. Its integrated ‘Where now?’ feature helps patients figure out their next steps and it encourages patients to connect and engage with your institution. Isabel SC recently ranked highest for accuracy in a large review of symptom checkers published in the BMJ.

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Isabel Active Intelligence

  • Isabel Active Intelligence (Isabel AI) provides automatic diagnostic decision support from within the EMR and requires no additional data input from case note extraction to providing a differential.

  • Diagnostic decision support in the EMR workflow is unlocked by extracting key information from patient notes containing contextually extracted symptoms and lab results.  These are sent to the Isabel engine embedded within the EMR to produce a differential diagnosis for the Clinician to work up.

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Isabel Clinical Educator

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Isabel Clinical Educator is a powerful case-based learning platform for developing, measuring and honing critical diagnosis reasoning skills in clinical learners.

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